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If you're living with primary sclerosing cholangitis (PSC), we're glad you're here.

This site is for patients, caregivers, families, physicians, and medical researchers.

Primary Sclerosing Cholangitis is a rare liver and bile duct disease which may have an autoimmune component. It's not curable, but some of the symptoms are treatable - and there's hope.

PSC is often associated with ulcerative colitis, Crohn’s disease, and related gastrointestinal and autoimmune diseases. Some PSC patients eventually require a liver transplant. Many PSCers, despite daily limitations and medications, are able to live full lives.

You probably never heard of PSC. It’s a frightening diagnosis. The medical system is intimidating. The diagnostic tests can be daunting; the future may look uncertain.

Yet, there’s hope. It’s not easy having PSC, but we can help you navigate the twists and turns. Those photos at the top of this page? They’re not models. They’re real people who have PSC and are still living their lives to the fullest. They're our members and our friends who remind us daily that life is more than just a PSC diagnosis.

We are a growing, unique, volunteer organization and we WILL find a cure. We include laypeople, medical professionals, and researchers. We offer education and support, with a strong emphasis on continuing to fund research on the disease. Read some comments by members about how our group support has helped them manage by clicking here.

We’re together in the fight, whatever it takes. And it takes a lot to battle PSC.

It takes research, it takes money, it takes all of us—patients, caregivers, families, passionate volunteers, and educated physicians and researchers—to find better treatment and a cure.

Read our stories, learn about the disease; get tips on coping and how to talk to your doctor.  Join a discussion and/or support group, check out our newsletter, The Duct.  Attend our annual conference, and help raise funds to research a cure.

Working together to provide research, education, and support for people affected by primary sclerosing cholangitis.